5 (6) -Carboxy-2',7'-dichlorofluorescein diacetate
Selected Variant
HY-D1078-01
Size: 5 mg
5 (6) -Carboxy-2',7'-dichlorofluorescein diacetate is a cell permeant fluorescent indicator. 5 (6) -Carboxy-2',7'-dichlorofluorescein diacetate can be used to assess reactive oxygen species (ROS) generation within human neuronal-glial (HNG) cells in primary co-culture[1]
Product Specifications
CAS Number
127770-45-0
UNSPSC
12171500
Hazard Statement
H315, H319, H335
Target
Reactive Oxygen Species (ROS)
Type
Dye Reagents
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-6-carboxy-2-7-dichlorofluorescein-diacetate.html
Purity
97.5
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
ClC1=C(OC(C)=O)C=C2OC3=CC(OC(C)=O)=C(Cl)C=C3C(OC4=O)(C5=CC=C(C(O)=O)C=C54)C2=C1.ClC6=C(OC(C)=O)C=C7OC8=CC(OC(C)=O)=C(Cl)C=C8C(OC9=O)(C%10=CC(C(O)=O)=CC=C%109)C7=C6
Molecular Formula
C25H14Cl2O9
Molecular Weight
529.28
Precautions
H315, H319, H335
References & Citations
[1]Pogue AI, et al. Metal-sulfate induced generation of ROS in human brain cells: detection using an isomeric mixture of 5- and 6-carboxy-2',7'-dichlorofluorescein diacetate (carboxy-DCFDA) as a cell permeant tracer. Int J Mol Sci. 2012;13 (8) :9615-26.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
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