Anti-Corticotropin Releasing Factor Antibody

Mouse Monoclonal Antibody specific to Corticotropin Releasing Factor

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Corticotropin-releasing factor, CRF, Corticotropin-releasing hormone

Gene Name

CRH

NCBI Gene ID

UniProt

P06850

Cellular Locus

Secreted

Host

Mouse

Reactivity

Human, Rat

Immunogen

Purified human/rat corticotropin-releasing factor (CRF, Sigma).

Target Antigen

Corticoliberin

Target

Corticotropin Releasing Factor

Clonality

Monoclonal

Isotype

IgG1

Type

Antibody

Applications

ELISA

Field of Research

Neuroscience

Purification Method

Purified by immunoaffinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium which is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Function

Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity). {UniProtKB:P06296, UniProtKB:Q8CIT0}.

Additionnal Information

These antibodies may be used in immunoassays to detect and quantitate CRF. Other applications are under investigation.

Storage Conditions

These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

Specificity

These antibodies react specifically with CRF. There is no cross-reactivity with bovine serum albumin, insulin, ovalbumin, or epidermal growth factor. These two antibodies recognize different epitopes on CRF. Dissociation constants = 10-9 M for 56101and 1.5 x 10-8 M for 56102.