3-Hydroxybenzaldehyde

3-Hydroxybenzaldehyde (3-HBA) is a precursor compound for phenolic compounds like Protocatechuic aldehyde (PCA) (HY-N0295) . 3-Hydroxybenzaldehyde, produced by 3-hydroxybenzyl-alcohol dehydrogenase, is a substrate of aldehyde dehydrogenase (ALDH) in rats and humans. 3-Hydroxybenzaldehyde has vasculoprotective effects in vitro and in vivo. 3-Hydroxybenzaldehyde is proming for research of atherosclerosis[1][2][3][4].

Product Specifications

CAS Number

[100-83-4]

Product Name Alternative

M-Hydroxybenzaldehyde

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Aldehyde Dehydrogenase (ALDH) ; NF-κB; p38 MAPK

Type

Natural Products

Related Pathways

MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/3-hydroxybenzaldehyde.html

Purity

99.89

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=CC1=CC=CC(O)=C1

Molecular Formula

C7H6O2

Molecular Weight

122.12

Precautions

H315, H319

References & Citations

[1]Kong BS, et al. Vasculoprotective Effects of 3-Hydroxybenzaldehyde against VSMCs Proliferation and ECs Inflammation.PLoS One. 2016 Mar 22;11 (3) :e0149394.|[2]Paixão JA, et al. 3-Hydroxybenzaldehyde. Acta Crystallogr C. 2000 Nov;56 Pt 11:1348-50. |[3]Chen K Y, et al. Protective effect of benzaldehyde combined with albendazole against brain injury induced by Angiostrongylus cantonensis infection in mice[J]. International Journal of Antimicrobial Agents, 2023, 62 (5) : 106963.|[4]Muthu S, et al. Quantum chemical studies, vibrational analysis, molecular structure, first order hyper polarizability, NBO and HOMO-LUMO analysis of 3-hydroxybenzaldehyde and its cation[J]. Spectrochim Acta A Mol Biomol Spectrosc. 2013 Nov;115:789-99.