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Human ADRB2 Protein, Flag, His Tag (Detergent)

This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca (V) 1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor is also a transcription regulator of the alpha-synuclein gene, and together, both genes are believed to be associated with risk of Parkinson's Disease.

Product Specifications

Background

This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca (V) 1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor is also a transcription regulator of the alpha-synuclein gene, and together, both genes are believed to be associated with risk of Parkinson's Disease.

Specifications

This protein carries a flag tag at the N-terminus and a polyhistidine tag at the C-terminus. The protein has a calculated MW of 59.5 kDa.

Accession Number

P07550-1

Expression Region

Gly 2 - Gly 365

Host

HEK293

Target

ADRB2

Conjugation

Unconjugated

Tag

N-Flag & C-10xHis

Source

Human

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Purity

90%

Bioactivity

Immobilized Human ADRB2 Protein, Flag,His Tag (Cat. No. AD2-H52D3) at 1 μg/mL (100 μL/well) can bind Anti-ADRB2 antibody Rabbit IgG with a linear range of 0.02-1.25 μg/mL (QC tested).

Format

Liquid

Buffer

50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5

Additives

Glycerol

Molecular Weight

59.5 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

500ug*1

Host or Source

HEK293

Species

Human

Protein ID

P07550-1

Preservative

Glycerol

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