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AF488 DBCO

AF488 DBCO is a fluorescent dye that labels azide-containing biomolecules. DBCO is the bioorthogonal partner of azide that allows covalent coupling in the absence of copper. AF488 is a bright, photostable green fluorophore. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively[1][2].

Product Specifications

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/af488-dbco.html

Solubility

DMSO : 4.68 mg/mL (ultrasonic; warming)

Smiles

O=C(O)C1=C(C=CC(C(NCCCCCC(N2CC3=C(C#CC4=C2C=CC=C4)C=CC=C3)=O)=O)=C1)C5=C(C6=[O+]C7=C5C=CC(N)=C7S(=O)([O-])=O)C=CC(N)=C6S(=O)(O)=O.CCN(CC)CC

Molecular Formula

C48H49N5O11S2

Molecular Weight

936.06

References & Citations

[1]Elena Boero, et al. Purified complement C3b triggers phagocytosis and activation of human neutrophils via complement receptor 1. Sci Rep. 2023 Jan 6;13 (1) :274.|[2]Chakraborty S, Hu S Y, Wu S H, et al. The interaction affinity between vascular cell adhesion molecule-1 (VCAM-1) and very late antigen-4 (VLA-4) analyzed by quantitative FRET[J]. PLoS One, 2015, 10 (3) : e0121399.

Shipping Conditions

Room temperature

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Frequently Asked Questions

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