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CHIR 98024

CHIR 98024 (Compound L) is a glycogen synthase kinase 3 (GSK3) inhibitor with an EC50 of 0.2566 μM[1].

Product Specifications

CAS Number

[556813-39-9]

UNSPSC

12352005

Hazard Statement

H226, H314

Target

GSK-3

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR; Stem Cell/Wnt

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/chir-98024.html

Purity

99.20

Solubility

DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

NC1=NC(NCCNC2=NC=C(C3=NC=CN3)C(C4=CC=C(Cl)C=C4Cl)=N2)=CC=C1[N+]([O-])=O

Molecular Formula

C20H17Cl2N9O2

Molecular Weight

486.31

Precautions

H226, H314

References & Citations

[1]Stephen D. Harrison, et al. Methods and compositions for the treatment of ischemia. WO2003074072A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

GSK-3

Available Sizes

Curated Selection

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