CHIR 98024
CHIR 98024 (Compound L) is a glycogen synthase kinase 3 (GSK3) inhibitor with an EC50 of 0.2566 μM[1].
Product Specifications
CAS Number
556813-39-9
UNSPSC
12352005
Hazard Statement
H226, H314
Target
GSK-3
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/chir-98024.html
Purity
99.20
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NC1=NC(NCCNC2=NC=C(C3=NC=CN3)C(C4=CC=C(Cl)C=C4Cl)=N2)=CC=C1[N+]([O-])=O
Molecular Formula
C20H17Cl2N9O2
Molecular Weight
486.31
Precautions
H226, H314
References & Citations
[1]Stephen D. Harrison, et al. Methods and compositions for the treatment of ischemia. WO2003074072A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GSK-3
Available Sizes
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