Zinc Gluconate

Zinc Gluconate is a zinc supplement in the form of a gluconate salt, which plays a role in various physiological processes such as immune function, wound healing, and olfaction. Zinc Gluconate has a LD50 of 39.6 mg/kg in mice (Tail vein injection) . Zinc Gluconate can be used in the research of inflammation, zinc deficiency, colds, cancer, and nutritional supplements[1][2][3][4][5].

Product Specifications

CAS Number

[4468-02-4]

UNSPSC

12352300

Hazard Statement

H302

Target

NF-κB; PPAR; Toll-like Receptor (TLR)

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/zinc-gluconate.html

Purity

98.0

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

O=C1[O-][Zn+2]2([OH]C1C(C(C(CO)O)O)O)[O-]C(C(C(C(C(CO)O)O)O)[OH]2)=O

Molecular Formula

C12H22O14Zn

Molecular Weight

455.67

Precautions

H302

References & Citations

[1]Hao, Yahui, et al. Zinc gluconate and its side-effects in clinical use.|[2]Wang Y, et al. Protective effect of zinc gluconate on intestinal mucosal barrier injury in antibiotics and LPS-induced mice. Front Microbiol. 2024 May 23;15:1407091.|[3]Duncan-Lewis CA, et al. Effects of zinc gluconate and 2 other divalent cationic compounds on olfactory function in mice. Comp Med. 2011 Aug;61 (4) :361-5.|[4]Poiraud C, et al. Zinc gluconate is an agonist of peroxisome proliferator-activated receptor-α in the epidermis. Exp Dermatol. 2012 May;21 (5) :347-51.|[5]Wang YC, et al. Determination of the median lethal dose of zinc gluconate in mice and safety evaluation. BMC Pharmacol Toxicol. 2024 Feb 5;25 (1) :15.