[Leu31,Pro34]-Neuropeptide Y(human,rat,mouse) (TFA)
Product Specifications
UNSPSC Description
[Leu31,Pro34]-Neuropeptide Y(human,rat) TFA is a specific neuropeptide Y Y1 receptor agonist. [Leu31,Pro34]-Neuropeptide Y(human,rat) TFA slao activates Y4, Y5. [Leu31,Pro34]-Neuropeptide Y(human,rat) TFA can increase blood pressure in anesthetized rats and increases food intake[1][2].
Target Antigen
Neuropeptide Y Receptor
Type
Peptides
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/leu31-pro34-neuropeptide-y-human-rat-tfa.html
Purity
98.07
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
O=C(N1[C@@H](CCC1)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N2[C@@H](CCC2)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(N3[C@@H](CCC3)C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N4[C@@H](CCC4)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CCSC)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CC6=CC=C(C=C6)O)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC7=CNC=N7)C(N[C@@H](CC8=CC=C(C=C8)O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCNC(N)=N)C(N9[C@@H](CCC9)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC%10=CC=C(C=C%10)O)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC%11=CC=C(C=C%11)O)N.O=C(C(F)(F)F)O
Molecular Weight
4354.76
References & Citations
[1]K McCrea, et al. 2-36[K4,RYYSA(19-23)]PP a novel Y<sub>5</sub>-receptor preferring ligand with strong stimulatory effect on food intake. Regul Pept. 2000 Feb 8;87(1-3):47-58.|[2]J Fuhlendorff, et al. [Leu31, Pro34]neuropeptide Y: a specific Y<sub>1</sub> receptor agonist. Proc Natl Acad Sci U S A. 1990 Jan;87(1):182-6.|[3]A Kask, et al. Evidence for involvement of neuropeptide Y receptors in the regulation of food intake: studies with Y<sub>1</sub>-selective antagonist BIBP3226. Br J Pharmacol. 1998 Aug;124(7):1507-15.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1323A/Leu31-Pro34-Neuropeptide-Y-human-rat-mouse-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1323A/Leu31-Pro34-Neuropeptide-Y-human-rat-mouse-TFA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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