2-Naphthol-d7

2-Naphthol-d7 is the deuterium labeled 2-Naphthol[1]. 2-Naphthol is a metabolite of naphthalene, catalyzed by cytochrome P450 (CYP) isozymes (CYP 1A1, CYP 1A2, CYP 2A1, CYP 2E1 and CYP 2F2) [2].

Product Specifications

CAS Number

[78832-54-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Purity

99.37

Solubility

10 mM in DMSO

Smiles

OC1=C([2H])C2=C(C([2H])=C([2H])C([2H])=C2[2H])C([2H])=C1[2H]

Molecular Formula

C10HD7O

Molecular Weight

151.22

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Kapuci M, et al. Determination of cytotoxic and genotoxic effects of naphthalene, 1-naphthol and 2-naphthol on human lymphocyte culture. Toxicol Ind Health. 2014 Feb;30 (1) :82-9.