Thiobis-β-Galactose-propyne

Thiobis-β-Galactose-propyne is an effective multivalent galectin-3 (Gal-3) inhibitor. Galectin-3 is involved in many metabolism processes related to cancer. Galectin-3-IN-1 is a click chemistry reagent. It contains an alkyne group that can undergo a copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction with molecules that have an azide group[1].

Product Specifications

CAS Number

[1989627-40-8]

UNSPSC

12352005

Target

Galectin

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/thiobis-β-galactose-propyne.html

Purity

99.76

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@H]([C@H]([C@H]([C@H](O1)CO)O)OCC#C)[C@@H]1S[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)OCC#C)O

Molecular Formula

C18H26O10S

Molecular Weight

434.46

References & Citations

[1]David Vrbata, et al. Glycopolymers Decorated with 3- O-Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3. J Med Chem. 2022 Mar 10;65 (5) :3866-3878.