Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Taltobulin intermediate-4

Taltobulin intermediate-4 is an intermediate in the synthesis of Taltobulin. Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].

Product Specifications

CAS Number

187345-37-5

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

ADC Payload

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/taltobulin-intermediate-4.html

Purity

99.86

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C)[C@@H](/C=C(C)/C(OCC)=O)N(C([C@H](C(C)(C)C)NC(OC(C)(C)C)=O)=O)C

Molecular Formula

C22H40N2O5

Molecular Weight

412.56

Precautions

H302, H315, H319, H335

References & Citations

[1]Loganzo F, et al. HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Cancer Res. 2003 Apr 15;63 (8) :1838-45.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

RbAp46 (RBBP7) Rabbit Polyclonal Antibody
TA380756 100 µL

RbAp46 (RBBP7) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Presenilin 1 / PS-1 Rabbit polyclonal Antibody
ER1915-40 100 µL

Presenilin 1 / PS-1 Rabbit polyclonal Antibody

Sign In for Pricing
View Details
COASY Recombinant Rabbit Monoclonal Antibody [JE58-56]
HA721128 100 µL

COASY Recombinant Rabbit Monoclonal Antibody [JE58-56]

Sign In for Pricing
View Details
GPR137C (NM_001099652) Human Over-expression Lysate
LY420474 100 µg

GPR137C (NM_001099652) Human Over-expression Lysate

Sign In for Pricing
View Details
OR5AP2 Antibody
8G473-AAT 50 µg

OR5AP2 Antibody

Sign In for Pricing
View Details
PAI1 (SERPINE1) (NM_000602) Human Over-expression Lysate
LY424612 100 µg

PAI1 (SERPINE1) (NM_000602) Human Over-expression Lysate

Sign In for Pricing
View Details