IL-20R beta, Mouse (HEK293, His)
IL-20R beta Protein (IL20RB) is the beta subunit of IL-20 receptor, forms functional heterodimers with different subunit protein and involves in STAT3 activation pathway[1]. The IL-20RA/IL-20RB dimer is a receptor for IL-19, IL-20 and IL-24. The IL-22RA1/IL-20RB dimer is a receptor for IL-20 and IL-24[2]. IL-20R beta Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal hFc-tag.
Product Specifications
Product Name Alternative
IL-20R beta Protein, Mouse (HEK293, His), Mouse, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/il-20r-beta-protein-mouse-hek293-his.html
Purity
98.0
Molecular Formula
213208 (Gene_ID) E9Q9A6/NP_001028715 (V27-S225) (Accession)
Molecular Weight
Approximately 23.8 kDa.
References & Citations
[1]Blumberg H, et al. Interleukin 20: discovery, receptor identification, and role in epidermal function. Cell. 2001 Jan 12;10 4 (1) :9-19.|[2]Wegenka UM. IL-20: biological functions mediated through two types of receptor complexes. Cytokine Growth Factor Rev. 2010 Oct;21 (5) :353-63.|[3]Sheikh F, et al. Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2. J Immunol. 2004 Feb 15;172 (4) :2006-10.|[4]Wang M, et al. Interleukin-24 and its receptors. Immunology. 2005 Feb;114 (2) :166-70.|[5]Wahl C, et al. IL-20 receptor 2 signaling down-regulates antigen-specific T cell responses. J Immunol. 2009 Jan 15;182 (2) :802-10.
Shipping Conditions
Dry ice.
Storage Conditions
Stored at -80°C for 1 year
Scientific Category
Recombinant Proteins
Available Sizes
Frequently Asked Questions
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