DMT-dC (bz) Phosphoramidite

DMT-dC (bz) Phosphoramidite is a deoxycytidine phosphoramide monomer with a protective group. DMT-dC (bz) Phosphoramidite is commonly used for synthesizing DNA dimers or trimers[1][2].

Product Specifications

CAS Number

[102212-98-6]

UNSPSC

12352200

Hazard Statement

H317

Target

DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog

Type

Biochemical Assay Reagents

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dmt-dc-bz-phosphoramidite.html

Purity

99.70

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)C[C@H](N5C(N=C(NC(C6=CC=CC=C6)=O)C=C5)=O)O4

Molecular Formula

C46H52N5O8P

Molecular Weight

833.91

Precautions

H317

References & Citations

[1]Thorpe JD, et al. Mechanochemical Synthesis of Short DNA Fragments. Chemistry. 2020 Jul 22;26 (41) :8857-8861.|[2]Johnston C, et al. Investigations into the synthesis of a nucleotide dimer via mechanochemical phosphoramidite chemistry. R Soc Open Sci. 2021 Mar 31;8 (3) :201703.