GalNAc-L96

GalNAc-L96, a triantennary N-acetylgalactosamine (GalNAc), is a ligand of asialoglycoprotein receptor (ASGPR) . GalNAc-L96 can be used to synthesize GalNAc-siRNA and can be used for oligonucleotide delivery[1].

Product Specifications

CAS Number

[1159408-62-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Drug Intermediate

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/galnac-l96.html

Purity

97.0

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(CCCCCCCCCCC(N1[C@H](COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)C[C@@H](OC(CCC(O)=O)=O)C1)=O)NC(COCCC(NCCCNC(CCCCO[C@H]5[C@H](NC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](COC(C)=O)O5)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]6[C@H](NC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](COC(C)=O)O6)=O)=O)COCCC(NCCCNC(CCCCO[C@H]7[C@H](NC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](COC(C)=O)O7)=O)=O.CCN(CC)CC

Molecular Formula

C127H194N12O45

Molecular Weight

2608.95

Precautions

H302, H315, H319

References & Citations

[1]Anna Clua, et al. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes. Molecules. 2022 Jun 20;27 (12) :3944.