(S, R, S) -AHPC-Boc
(S, R, S) -AHPC-Boc (VH032-Boc) is a ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S, R, S) -AHPC-Boc is used in PROTAC technology[1].
Product Specifications
CAS Number
[1448189-98-7]
Product Name Alternative
VH032-Boc
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-r-s-ahpc-boc.html
Purity
99.15
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC(C)(C)C)N[C@@H](C(C)(C)C)C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O
Molecular Formula
C27H38N4O5S
Molecular Weight
530.68
Precautions
H315, H319
References & Citations
[1]Zengerle M, et al. Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4. ACS Chem Biol. 2015;10 (8) :1770‐1777.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Monoclonal COX5b Antibody (021) [HRP]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
Eukaryotic Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40)
Eukaryotic Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40)
Eukaryotic Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40)
Eukaryotic Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40)