Atrimustine
Atrimustine is a conjugate of chlorambucil and β-estradiol benzoate with the antitumor activity.
Product Specifications
CAS Number
75219-46-4
Product Name Alternative
Bestrabucil; KM2210
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Atrimustine.html
Purity
98.88
Solubility
DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C[C@@]1([C@H]2OC(COC(CCCC3=CC=C(N(CCCl)CCCl)C=C3)=O)=O)[C@](CC2)([H])[C@@](CCC4=CC(OC(C5=CC=CC=C5)=O)=CC=C64)([H])[C@]6([H])CC1
Molecular Formula
C41H47Cl2NO6
Molecular Weight
720.72
References & Citations
[1]Ezaki K, et al. A combination trial of human lymphoblastoid interferon and bestrabucil (KM2210) for adult T-cell leukemia-lymphoma. Cancer. 1991 Aug 15;68 (4) :695-8.|[2]Akaza H, et al. Inhibitory effects of bestrabucil, a conjugate of chlorambucil and estradiol, on the production of androgen-induced growth factor (s) by Shionogi carcinoma 115 cells. Int J Urol. 1994 Mar;1 (1) :67-73.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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