Thozalinone
Thozalinone is an orally active antidepressant agent. Thozalinone induces the release of Norepinephrine (HY-13715) and dopamine[1][2].
Product Specifications
CAS Number
[655-05-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/thozalinone.html
Purity
99.93
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1N=C(N(C)C)OC1C2=CC=CC=C2
Molecular Formula
C11H12N2O2
Molecular Weight
204.23
Precautions
H302, H315, H319, H335
References & Citations
[1]Greenblatt EN, et al. Some pharmacologic properties of thozalinone, a new excitant. Toxicol Appl Pharmacol. 1965 Jul;7 (4) :566-78. |[2]Yen-Koo HC, et al. Inhibition of dopaminergic agonist-induced gnawing behavior by neuroleptic drugs in mice. Drug Chem Toxicol. 1985;8 (6) :495-502.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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