RAR/RXR agonist-1

RAR/RXR agonist-1 (compound 7) is a chlorinated retinoic acid isomer, a selective RARα agonist and a partial RXRα agonist. RAR/RXR agonist-1 can activate RXRα and induce G2/M arrest and apoptosis in cancer cells[1].

Product Specifications

UNSPSC

12352005

Target

Apoptosis; RAR/RXR

Type

Reference compound

Related Pathways

Apoptosis; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rar-rxr-agonist-1.html

Smiles

CC(CCC1(C)C)(C)C2=C1C=C(C)C(C(/C(Cl)=C/C3=CC=C(C(O)=O)C=C3)=O)=C2

Molecular Formula

C25H27ClO3

Molecular Weight

410.93

References & Citations

[1]Halogenated retinoid derivatives as dual RARα and RXRα modulators for treating acute promyelocytic leukemia cells

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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