RAR/RXR agonist-1
RAR/RXR agonist-1 (compound 7) is a chlorinated retinoic acid isomer, a selective RARα agonist and a partial RXRα agonist. RAR/RXR agonist-1 can activate RXRα and induce G2/M arrest and apoptosis in cancer cells[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; RAR/RXR
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rar-rxr-agonist-1.html
Smiles
CC(CCC1(C)C)(C)C2=C1C=C(C)C(C(/C(Cl)=C/C3=CC=C(C(O)=O)C=C3)=O)=C2
Molecular Formula
C25H27ClO3
Molecular Weight
410.93
References & Citations
[1]Halogenated retinoid derivatives as dual RARα and RXRα modulators for treating acute promyelocytic leukemia cells
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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