Erythromycin Ethylsuccinate

Erythromycin Ethylsuccinate is an antibiotic useful for the treatment of a number of bacterial infections, has an antimicrobial spectrum similar to or slightly wider than that of penicillin. Erythromycin Ethylsuccinate has antiviral activity against HIV-1.

Product Specifications

CAS Number

[1264-62-6]

Product Name Alternative

Erythromycin ethyl succinate; EES

UNSPSC

12352005

Hazard Statement

H317, H334

Target

Antibiotic; Autophagy; Bacterial; HIV

Type

Natural Products

Related Pathways

Anti-infection; Autophagy

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Erythromycin-Ethylsuccinate.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : ≥ 50 mg/mL|Ethanol : ≥ 33.33 mg/mL

Smiles

O=C(CCC(OCC)=O)O[C@H]([C@H]1N(C)C)[C@](O[C@H](C)C1)([H])O[C@@H]([C@](O)(C[C@H](C([C@@H]([C@@H](O)[C@@]2(O)C)C)=O)C)C)[C@H]([C@@H]([C@H](C(O[C@@H]2CC)=O)C)O[C@@](O[C@@H](C)[C@@H]3O)([H])C[C@@]3(C)OC)C

Molecular Formula

C43H75NO16

Molecular Weight

862.05

Precautions

H317, H334

References & Citations

[1]Gustafsson A, et al. The association of erythromycin ethylsuccinate with acute colitis in horses in Sweden. Equine Vet J. 1997 Jul;29 (4) :314-8.|[2]Feng YC, et al. Construction of universal quantitative models for determination of roxithromycin and erythromycin ethylsuccinate in tablets from different manufacturers using near infrared reflectance spectroscopy. J Pharm Biomed Anal. 2006 May 3;41 (2) :373-84.|[3]Komuro I, et al. Erythromycin derivatives inhibit HIV-1 replication in macrophages through modulation of MAPK activity to induce small isoforms of C/EBPbeta. Proc Natl Acad Sci U S A. 2008 Aug 26;105 (34) :12509-14.