2-Ketoglutaric acid
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM) [1].
Product Specifications
CAS Number
328-50-7
Product Name Alternative
Alpha-Ketoglutaric acid; 2-Oxoglutaric acid
UNSPSC
12352211
Hazard Statement
H314, H318
Target
Endogenous Metabolite; Tyrosinase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/2-Ketoglutaric_acid.html
Purity
99.90
Solubility
DMSO : 250 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
Smiles
O=C(C(O)=O)CCC(O)=O
Molecular Formula
C5H6O5
Molecular Weight
146.10
Precautions
H314, H318
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite; Microbial Metabolite
Available Sizes
Frequently Asked Questions
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