BCR-ABL1-IN-1
BCR-ABL1-IN-1 (Example 74) is the inhibitor for ABL1 (64-515) with IC50 of 8.7 nM[1].
Product Specifications
CAS Number
[1488090-21-6]
UNSPSC
12352005
Target
Bcr-Abl
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcr-abl1-in-1.html
Purity
99.82
Solubility
DMSO : 175 mg/mL (ultrasonic)
Smiles
O=C(C1=CN=CC(C2=CC=CN=C2)=C1)NC3=CC=C(C=C3)OC(F)(F)F
Molecular Formula
C18H12F3N3O2
Molecular Weight
359.30
References & Citations
[1]P. Furet, et al., Compounds and compositions for inhibiting the activity of abl1, abl2 and bcr-abl1. WO2013171641
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Abl
Available Sizes
Curated Selection
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