Isoviolanthin (Standard)

Isoviolanthin (Standard) is the analytical standard of Isoviolanthin (HY-N6896) . This product is intended for research and analytical applications. Isoviolanthin is a flavonoid glycoside. Isoviolanthin can be extracted from Dendrobium officinale. Isoviolanthin has a strong affinity for binding to KDM6B, CHAC2, ESCO2, and IPO4. Isoviolanthin decreases MMP-2 and MMP-9. Isoviolanthin inhibits TGF-β/Smad and PI3K/Akt/mTOR signaling pathways. Isoviolanthin increases Fhl3 expression. Isoviolanthin has cytoprotective effects. Isoviolanthin has anticancer activity against hepatocellular carcinoma[1][2][3].

Product Specifications

CAS Number

[40788-84-9]

UNSPSC

12352005

Target

Akt; Histone Demethylase; MMP; mTOR; PI3K; Reference Standards; TGF-beta/Smad

Type

Reference Standards

Related Pathways

Epigenetics; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR; Stem Cell/Wnt; TGF-beta/Smad

Field of Research

Cancer; Endocrinology

Assay Protocol

https://www.medchemexpress.com/isoviolanthin-standard.html

Smiles

OC1=C([C@H]2[C@@H]([C@@H]([C@@H](O)[C@H](C)O2)O)O)C(O)=C(C(C=C(C3=CC=C(O)C=C3)O4)=O)C4=C1[C@@H]5O[C@@H]([C@@H](O)[C@H](O)[C@H]5O)CO

Molecular Formula

C27H30O14

Molecular Weight

578.52

References & Citations

[1]Xing S, et al. Isoviolanthin Extracted from Dendrobium officinale Reverses TGF-β1-Mediated Epithelial⁻Mesenchymal Transition in Hepatocellular Carcinoma Cells via Deactivating the TGF-β/Smad and PI3K/Akt/mTOR Signaling Pathways. Int J Mol Sci. 2018 May 23;19 (6) .