Pyrimidyn 7
Product Specifications
UNSPSC Description
Pyrimidyn 7 is an inhibitor of dynamin I/II with IC50 values of 1.1 μM and 1.8 μM, respectively. Pyrimidyn 7 competitively inhibits the interactions between GTP and phospholipids with dynamin I. Additionally, Pyrimidyn 7 reversibly inhibits clathrin-mediated endocytosis (CME) of transferrin and epidermal growth factor (EGF) in various non-neuronal cell linecell[1.
Target Antigen
Dynamin
Type
Reference compound
Related Pathways
Cytoskeleton
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pyrimidyn-7.html
Smiles
CC1=CC(NCCCCCCCCCCCC)=NC(NCCN(C)C)=N1
Molecular Weight
363.58
References & Citations
[1]McGeachie AB, et al. Pyrimidyn compounds: dual-action small molecule pyrimidine-based dynamin inhibitors. ACS Chem Biol. 2013 Jul 19;8(7):1507-18.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-122564/Pyrimidyn-7-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-122564/
Clinical Information
No Development Reported
CAS Number
1440126-94-2
Curated Selection
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