JQ-1 carboxylic acid-PEG3-C2-NH2
JQ-1 carboxylic acid-PEG3-C2-NH2 is a E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACT[1].
Product Specifications
CAS Number
[2098790-24-8]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jq-1-carboxylic-acid-peg3-c2-nh2.html
Purity
99.39
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NCCOCCOCCOCCNC(C[C@@H]1N=C(C2=CC=C(Cl)C=C2)C3=C(SC(C)=C3C)N4C(C)=NN=C14)=O
Molecular Formula
C27H35ClN6O4S
Molecular Weight
575.12
References & Citations
[1]Tao Y, et, al. Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1. J Am Chem Soc. 2022 Oct 12;144 (40) :18688-18699.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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