VMAT2-IN-4
VMAT2-IN-4 (compound 11) is a vesicular monoamine transporter-2 (VMAT2) inhibitor. VMAT2-IN-4 inhibits [3H]-DTBZ binding (Ki = 560 nM) . VMAT2-IN-4 inhibits [3H]-DA (Ki = 45 nM) from entering vesicles and being taken up by cells. VMAT2-IN-4 can be used in methamphetamine addiction research[1].
Product Specifications
CAS Number
1436695-49-6
UNSPSC
12352005
Target
Monoamine Transporter
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/vmat2-in-4.html
Smiles
OC[C@H](O)CN1[C@@H](CCC2=CC=C(OC(F)F)C=C2)CC[C@H]1CCC3=CC=C(OC(F)F)C=C3.[H]Cl
Molecular Formula
C25H32ClF4NO4
Molecular Weight
521.97
References & Citations
[1]Penthala NR, et al. Pyrrolidine analogs of GZ-793A: synthesis and evaluation as inhibitors of the vesicular monoamine transporter-2 (VMAT2) . Bioorg Med Chem Lett. 2013 Jun 1;23 (11) :3342-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K4309106 1.0 µg DNA
Olfr670 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
Sign In for Pricing
View Details ![Mouse Monoclonal Cyclin D1 Antibody (SPM587) [Biotin]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
NBP2-34816B 0.1 mL
Mouse Monoclonal Cyclin D1 Antibody (SPM587) [Biotin]
Sign In for Pricing
View Details 
