L-012
L-012 is a luminal-based chemiluminescent probe. L-012 sodium salt can detect NADPH oxidase (Nox) -derived superoxide and nitrogen species (reactive oxygen species (ROS) and reactive nitrogen species (RNS) ) [1][2].
Product Specifications
CAS Number
143323-55-1
UNSPSC
12352005
Target
Fluorescent Dye
Type
Reference compound
Related Pathways
Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/l-012.html
Purity
99.63
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=C2C(Cl)=NC(C3=CC=CC=C3)=C1N)NNC2=O
Molecular Formula
C13H9ClN4O2
Molecular Weight
288.69
References & Citations
[1]Kielland A, et al. In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012. Free Radic Biol Med. 2009;47 (6) :760-766.|[2]Imada I, et al. Analysis of reactive oxygen species generated by neutrophils using a chemiluminescence probe L-012[J]. Analytical biochemistry, 1999, 271 (1) : 53-58.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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