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L-012

L-012 is a luminal-based chemiluminescent probe. L-012 sodium salt can detect NADPH oxidase (Nox) -derived superoxide and nitrogen species (reactive oxygen species (ROS) and reactive nitrogen species (RNS) ) [1][2].

Product Specifications

CAS Number

143323-55-1

UNSPSC

12352005

Target

Fluorescent Dye

Type

Reference compound

Related Pathways

Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/l-012.html

Purity

99.63

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=C2C(Cl)=NC(C3=CC=CC=C3)=C1N)NNC2=O

Molecular Formula

C13H9ClN4O2

Molecular Weight

288.69

References & Citations

[1]Kielland A, et al. In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012. Free Radic Biol Med. 2009;47 (6) :760-766.|[2]Imada I, et al. Analysis of reactive oxygen species generated by neutrophils using a chemiluminescence probe L-012[J]. Analytical biochemistry, 1999, 271 (1) : 53-58.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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