CDFI
CDFI is an inhibitor of the lipid II flippase MurJ. CDFI potentiates the activity of β-lactams against MRSA[1][2].
Product Specifications
CAS Number
[1199797-92-6]
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cdfi.html
Purity
99.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC1=CC2=C(NC(C3=C(Cl)C=CC=C3)=C2C4CCN(CC4)CC5=C(C)C(C)=CC=C5)C=C1
Molecular Formula
C28H28ClFN2
Molecular Weight
446.99
References & Citations
[1]Fernandes PB, et al. Revisiting the Role of VraTSR in Staphylococcus aureus Response to Cell Wall-Targeting Antibiotics. J Bacteriol. 2022 Aug 16;204 (8) :e0016222.|[2]Dhanda G, et al. Antibiotic Adjuvants: A Versatile Approach to Combat Antibiotic Resistance. ACS Omega. 2023 Mar 14;8 (12) :10757-10783.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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