TMX-4113
TMX-4113 is a degrader of phosphodiesterase 6D (PDE6D) and casein kinase 1α (CK1α) . TMX-4113 can be used for the research of cancer[1].
Product Specifications
CAS Number
2766385-92-4
UNSPSC
12352005
Target
Casein Kinase; Molecular Glues; Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; PROTAC; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tmx-4113.html
Purity
99.08
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C(N1N=NC(C2=CSC=C2SC)=C1)CC3)NC3=O
Molecular Formula
C12H12N4O2S2
Molecular Weight
308.38
References & Citations
[1]Teng M, et al. Development of PDE6D and CK1α Degraders through Chemical Derivatization of FPFT-2216. J Med Chem. 2022 Jan 13;65 (1) :747-756.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK1; PDE6
Available Sizes
Frequently Asked Questions
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