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VEGFR-2-IN-57

VEGFR-2-IN-57 (compound 6n) exhibited significant cytotoxicity in HUVEC cells (IC50 = 28.77 nM) .

Product Specifications

UNSPSC

12352005

Target

VEGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/vegfr-2-in-57.html

Smiles

O=C(NC1=CC=C(OC)C=C1)CCN2CCC(C(N/N=C3C(NC4=C\3C=C(OC)C=C4)=O)=O)CC2

Molecular Formula

C25H29N5O5

Molecular Weight

479.53

References & Citations

[1]Eldehna WM, et al. Design, synthesis, and in silico insights of novel N'- (2-oxoindolin-3-ylidene) piperidine-4-carbohydrazide derivatives as VEGFR-2 inhibitors. Bioorg Chem. 2024 Dec;153:107829.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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