VEGFR-2-IN-57
VEGFR-2-IN-57 (compound 6n) exhibited significant cytotoxicity in HUVEC cells (IC50 = 28.77 nM) .
Product Specifications
UNSPSC
12352005
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vegfr-2-in-57.html
Smiles
O=C(NC1=CC=C(OC)C=C1)CCN2CCC(C(N/N=C3C(NC4=C\3C=C(OC)C=C4)=O)=O)CC2
Molecular Formula
C25H29N5O5
Molecular Weight
479.53
References & Citations
[1]Eldehna WM, et al. Design, synthesis, and in silico insights of novel N'- (2-oxoindolin-3-ylidene) piperidine-4-carbohydrazide derivatives as VEGFR-2 inhibitors. Bioorg Chem. 2024 Dec;153:107829.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog