BAR501
BAR501 is a potent and selective agonist of GPBAR1 with an EC50 of 1 μM.
Product Specifications
CAS Number
1632118-69-4
UNSPSC
12352211
Target
G protein-coupled Bile Acid Receptor 1
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/BAR501.html
Purity
99.90
Solubility
DMSO : ≥ 50 mg/mL|Ethanol : 120 mg/mL (ultrasonic)
Smiles
C[C@H](CCCO)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@@H](O)[C@@H](CC)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
Molecular Formula
C26H46O3
Molecular Weight
406.64
References & Citations
[1]Renga B, et al. Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1. PLoS One. 2015 Nov 5;10 (11) :e0141082.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
135277 1 Pack (1 Panel (s) x 1 Pack)
E/E057/NT-SA-148X148/1-B Facility & Office Signs & Labels (Adhesive)
Sign In for Pricing
View Details MBS7086099-01 0.02 mg (E-Coli)
Recombinant Agelena orientalis U2-agatoxin-Ao1u
Sign In for Pricing
View Details MBS7086099-02 0.1 mg (E-Coli)
Recombinant Agelena orientalis U2-agatoxin-Ao1u
Sign In for Pricing
View Details MBS7086099-03 0.02 mg (Yeast)
Recombinant Agelena orientalis U2-agatoxin-Ao1u
Sign In for Pricing
View Details MBS7086099-04 0.1 mg (Yeast)
Recombinant Agelena orientalis U2-agatoxin-Ao1u
Sign In for Pricing
View Details MBS7086099-05 0.02 mg (Baculovirus)
Recombinant Agelena orientalis U2-agatoxin-Ao1u
Sign In for Pricing
View Details