Hi 76-0079
Hi 76-0079 (NNC0076-0079; 76-0079) is a lipase inhibitor that specifically targets hormone-sensitive lipase (HSL). Hi 76-0079 inhibits PNPB Hydrolysis in cell lysates of HEK293A cells overexpressing Lipe with an IC50 value of 0.1 μM. Hi 76-0079 synergizes with the ATGL inhibitor Atglistatin to block lipolysis in vitro. Hi 76-0079 can be used for the study of lipid metabolism[1][2].
Product Specifications
CAS Number
374567-94-9
Product Name Alternative
NNC0076-0079; 76-0079
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Lipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hi-76-0079.html
Purity
99.90
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(NN1CCOCC1)OC2=CC=C(C=C2)Cl
Molecular Formula
C11H13ClN2O3
Molecular Weight
256.69
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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