Wnt/β-catenin-IN-2

Wnt/β-catenin-IN-2 (Compound 3235-0367) is a Wnt/β-catenin signaling pathway inhibitor, with IC50 and KD values of 7.1 and 2.5 μM, respectively. Wnt/β-catenin-IN-2 can be used for the research of cancer[1].

Product Specifications

CAS Number

[1397006-01-7]

UNSPSC

12352005

Target

Wnt; β-catenin

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/wnt-β-catenin-in-2.html

Purity

99.46

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C=C1)OC)NC2=C(C(NC(C(C)C)C(NNC(COC3=CC=CC=C3)=O)=O)=O)C=CC=C2

Molecular Formula

C28H30N4O6

Molecular Weight

518.56

References & Citations

[1]Lee HJ, et al. Structure-based Discovery of Novel Small Molecule Wnt Signaling Inhibitors by Targeting the Cysteine-rich Domain of Frizzled. J Biol Chem. 2015 Dec 18;290 (51) :30596-606.