Lipiferolide
Product Specifications
UNSPSC Description
Lipiferolide is an antiplasmodial agent (IC50: 1.8 μg/mL) that can be isolated from Liriodendron tulipifera. Lipiferolide also inhibits FPTase, and has antitumor activity[1][2].
Target Antigen
Farnesyl Transferase; Parasite
Type
Natural Products
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/lipiferolide.html
Solubility
10 mM in DMSO
Smiles
C[C@]12[C@](O2)([H])[C@]3([H])[C@@](C(C(O3)=O)=C)([H])[C@@H](C/C(C)=C\CC1)OC(C)=O
Molecular Weight
306.35
References & Citations
[1]Graziose R, et al. Antiplasmodial activity of aporphine alkaloids and sesquiterpene lactones from Liriodendron tulipifera L. J Ethnopharmacol. 2011 Jan 7;133(1):26-30.|[2]Moon MK, et al. Farnesyl protein transferase and tumor cell growth inhibitory activities of lipiferolide isolated from Liriodendron tulipifera. Arch Pharm Res. 2007 Mar;30(3):299-302.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N3378/Lipiferolide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N3378/
Clinical Information
No Development Reported
CAS Number
41059-80-7
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