Creatine
Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain.
Product Specifications
CAS Number
57-00-1
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Dopamine Receptor; Endogenous Metabolite
Type
Natural Products
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/2-_1-Methylguanidino_acetic_acid.html
Concentration
10mM
Purity
99.95
Solubility
H2O : 6.25 mg/mL (ultrasonic)
Smiles
CN(C(N)=N)CC(O)=O
Molecular Formula
C4H9N3O2
Molecular Weight
131.13
Precautions
H302, H315, H319, H335
References & Citations
[1]Nouioua S, et al. Creatine deficiency syndrome. A treatable myopathy due to arginine-glycine amidinotransferase (AGAT) deficiency. Neuromuscul Disord. 2013 Aug;23 (8) :670-4.|[2]Gerber I, et al., Stimulatory effects of creatine on metabolic activity, differentiation and mineralization of primary osteoblast-like cells in monolayer and micromass cell cultures. Eur Cell Mater. 2005 Jul 15;10:8-22. |[3]Guidi C, et al., Differential effect of creatine on oxidatively-injured mitochondrial and nuclear DNA. Biochim Biophys Acta. 2008 Jan;1780 (1) :16-26. |[4]Cunha MP, et al., Antidepressant-like effect of creatine in mice involves dopaminergic activation. J Psychopharmacol. 2012 Nov;26 (11) :1489-501.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite; Microbial Metabolite
Available Sizes
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