LZCap AG(3'Acm) Cas9 mRNA
Product Specifications
UNSPSC Description
The Cas9 protein, guided by sgRNA, induces DNA double-strand breaks (DSBs) at specific genomic locations, activating the cell's endogenous DNA repair mechanisms, non-homologous end joining (NHEJ), or homology-directed repair (HDR), for repairing the targeted DSBs, enabling genome DNA target recognition and cleavage. LZCap AG(3'Acm) Cas9 mRNA can be used together with purified sgRNA for CRISPR/Cas genome editing, where the expressed Cas9 protein acts in conjunction with sgRNA to perform cleavage.
Target Antigen
CRISPR/Cas9
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/lzcap-ag-3-acm-cas9-mrna.html
Solubility
10 mM in H2O
Smiles
[LZCapAG(3'Acm)Cas9mRNA]
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Frequently Asked Questions
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