Atractylodinol
Atractylodinol, an antimicrobial, is a PRRSV (porcine reproductive and respiratory syndrome virus) inhibitor. Atractylodinol inhibits TGF-β receptor I recycling by binding to vimentin (KD of 454 nM) and inducing the formation of filamentous aggregates[1][2].
Product Specifications
CAS Number
61642-89-5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/atractylodinol.html
Solubility
10 mM in DMSO
Smiles
OC/C=C/C#CC#C/C=C/C1=CC=CO1
Molecular Formula
C13H10O2
Molecular Weight
198.22
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Mengjiao Hao, et al. Atractylodinol prevents pulmonary fibrosis through inhibiting TGF-β receptor 1 recycling by stabilizing vimentin. Mol Ther. 2023 Oct 4;31 (10) :3015-3033. |[2]Alyssa B Evans, et al. Identification and characterization of small molecule inhibitors of porcine reproductive and respiratory syndrome virus. Antiviral Res. 2017 Oct:146:28-35.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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