Sodium nitroprusside

Sodium nitroprusside (Ro 21-2498) is a potent vasodilator working through releasing NO spontaneously in blood.

Product Specifications

CAS Number

[14402-89-2]

Product Name Alternative

Ro 21-2498

UNSPSC

12352300

Hazard Statement

H301

Target

Angiotensin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Nitroprusside-Sodium.html

Concentration

10mM

Purity

99.17

Solubility

DMSO : 33.33 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

N#C[Fe-2](C#N)(C#N)(C#N)(N=O)C#N.[Na+].[Na+]

Molecular Formula

C5FeN6Na2O

Molecular Weight

261.92

Precautions

H301

References & Citations

[1]Wink, D.A., et al., The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: a direct correlation between nitric oxide formation and protection. Arch Biochem Biophys, 1996. 331 (2) : p. 241-8.|[2]Garg, U.C. and A. Hassid, Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest, 1989. 83 (5) : p. 1774-7.|[3]Namazi, H., Sodium nitroprusside as a nitric oxide donor in a rat intestinal ischemia reperfusion model: a novel molecular mechanism. Clinics (Sao Paulo), 2008. 63 (3) : p. 405.