MeAIB
MeAIB (α- (Methylamino) isobutyric acid) is a specific substrate for amino acid transport system A (ATA1) . ATA mediate the uptake of short-chain neutral amino acids in a Na+-dependent manner[1].
Product Specifications
CAS Number
2566-34-9
Product Name Alternative
α- (Methylamino) isobutyric acid
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Amino acid Transporter
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/α-methylamino-isobutyric-acid.html
Purity
98.0
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; adjust pH to 2 with 1M HCl; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)
Smiles
CC(C)(NC)C(O)=O
Molecular Formula
C5H11NO2
Molecular Weight
117.15
Precautions
H302, H315, H319, H335
References & Citations
[1]M Sugawara, et al. Structure and function of ATA3, a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal muscle. Biochim Biophys Acta. 2000 Dec 20;1509 (1-2) :7-13.|[2]Y Kudo, et al. Changes in expression and function of syncytin and its receptor, amino acid transport system B (0) (ASCT2), in human placental choriocarcinoma BeWo cells during syncytialization. Placenta. 2002 Aug;23 (7) :536-41.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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