MeAIB

MeAIB (α- (Methylamino) isobutyric acid) is a specific substrate for amino acid transport system A (ATA1) . ATA mediate the uptake of short-chain neutral amino acids in a Na+-dependent manner[1].

Product Specifications

CAS Number

[2566-34-9]

Product Name Alternative

α- (Methylamino) isobutyric acid

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Amino acid Transporter

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/α-methylamino-isobutyric-acid.html

Purity

98.0

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; adjust pH to 2 with 1M HCl; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)

Smiles

CC(C)(NC)C(O)=O

Molecular Formula

C5H11NO2

Molecular Weight

117.15

Precautions

H302, H315, H319, H335

References & Citations

[1]M Sugawara, et al. Structure and function of ATA3, a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal muscle. Biochim Biophys Acta. 2000 Dec 20;1509 (1-2) :7-13.|[2]Y Kudo, et al. Changes in expression and function of syncytin and its receptor, amino acid transport system B (0) (ASCT2), in human placental choriocarcinoma BeWo cells during syncytialization. Placenta. 2002 Aug;23 (7) :536-41.