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Thiomuscimol

Thiomuscimol is a GABAA receptor agonist (IC50=19 nM) . It has been used as a photoaffinity label for the purification and identification of GABA binding sites within the GABAA receptor complex.

Product Specifications

CAS Number

62020-54-6

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/thiomuscimol.html

Smiles

O=C1NSC(CN)=C1

Molecular Formula

C4H6N2OS

Molecular Weight

130.17

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Melikian, et al. Condensation of muscimol or thiomuscimol with aminopyridazines yields GABA-A antagonists. J. Med. Chem. 35 (22), 4092-4097 (1992) .

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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