Apraglutide (TFA)

Apraglutide TFA (FE 203799 TFA), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum[1].

Product Specifications

Product Name Alternative

FE 203799 (TFA)

UNSPSC

12352209

Target

GLP Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/apraglutide-tfa.html

Purity

98.69

Solubility

H2O : 66.67 mg/mL (ultrasonic; adjust pH to 11 with NaOH)

Smiles

[HGDGSFSDE-{Nle}-{d-Phe}-TILDLLAARDFINWLIQTKITD-NH2(TFAsalt)]

Molecular Formula

C172H263N43O52.xC2HF3O2

Molecular Weight

3765.25 (free base)

References & Citations

[1]Slim GM, et al. Novel Long-Acting GLP-2 Analogue, FE 203799 (Apraglutide), Enhances Adaptation and Linear Intestinal Growth in a Neonatal Piglet Model of Short Bowel Syndrome with Total Resection of the Ileum. JPEN J Parenter Enteral Nutr. 2019 Jan 6.