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Famotidine (GMP)

Famotidine GMP (MK-208 GMP) is Famotidine produced in GMP guideline. Famotidine GMP is a competitive histamine H2-receptor antagonist, inhibits gastric secretion, activates the gastric mucosal defensive mechanisms. Famotidine GMP ameliorates peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD/GORD) in rats model[1][2].

Product Specifications

CAS Number

76824-35-6

Product Name Alternative

MK-208 (GMP)

UNSPSC

12352005

Hazard Statement

H302-H315-H317-H319-H334-H335

Target

Histamine Receptor

Type

GMP Small Molecules

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/famotidine-gmp.html

Smiles

N=C(NS(=O)(N)=O)CCSCC1=CSC(NC(N)=N)=N1

Molecular Formula

C8H15N7O2S3

Molecular Weight

337.45

Precautions

P261-P264-P270-P271-P272-P280-P284-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Inan, A., et al., Effects of the histamine H2 receptor antagonist famotidine on the healing of colonic anastomosis in rats. Clinics (Sao Paulo), 2009. 64 (6) : p. 567-70. |[2]Miyata, K., et al., Studies on the mechanism for the gastric mucosal protection by famotidine in rats. Jpn J Pharmacol, 1991. 55 (2) : p. 211-22.

Shipping Conditions

Room temperature

Scientific Category

GMP Small Molecules

Clinical Information

No Development Reported

Frequently Asked Questions

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