PEP1

PEP1 is an amphipathic α-helical peptide containing 31 residues. PEP1 exhibits a concentration-dependent interaction with POPC-supported lipid bilayers (SLBs) : at low concentrations, it inserts into SLBs to generate compressive stress; at medium concentrations, it saturates the membrane surface, leading to constant stress; and at high concentrations, it solubilizes SLBs. PEP1 can be used in studies on the mechanism of membrane-peptide interactions[1].

Product Specifications

UNSPSC

12352209

Target

Liposome

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pep1.html

Purity

99.16

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(NCC(N[C@@H](CO)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC(O)=O)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CS)C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC7=CC=CC=C7)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC8=CNC9=CC=CC=C89)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC%10=CC=C(C=C%10)O)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N