Recombinant Ophiophagus hannah Cathelicidin-related peptide Oh-Cath
Product Specifications
Product Name Alternative
Cathelicidin-related antimicrobial peptide; Oh_CRAMP; Vipericidin
Abbreviation
Recombinant Ophiophagus hannah Cathelicidin-related peptide Oh-Cath protein
UniProt
B6S2X2
Expression Region
162-191aa
Organism
Ophiophagus hannah (King cobra) (Naja hannah)
Target Sequence
KFFKKLKNSVKKRAKKFFKKPRVIGVSIPF
Tag
N-terminal 6xHis-SUMO-tagged
Type
Developed Protein
Source
E.coli
Field of Research
Others
Relevance
Potent antimicrobial peptide against Gram-negative (MIC=0.25 ug/ml against E.coli ATCC 25922, MIC=0.5 ug/ml against P.aeruginosa) and Gram-positive bacteria (MIC=64 ug/ml against E.faecalis, MIC=64 ug/ml against S.aureus) . Adopts an amphipathic alpha helical conformation, that may allow to partition into the target membrane. Low hemolytic activities have been observed on mammalian cells.
Endotoxin
Not test
Purity
Greater than 95% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Molecular Weight
21.8 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Product MSDS
https://www.cusabio.com/msds/12936834/
Protein Length
Full Length of Mature Protein
Available Sizes
Curated Selection
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