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(Z) -PUGNAc

(Z) -PUGNAc is a potent O-GlcNAcase inhibitor. (Z) -PUGNAc is a vastly more potent inhibitor of O-GlcNAcase than the E form[1].

Product Specifications

CAS Number

132489-69-1

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

OGA

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/z-pugnac.html

Concentration

10mM

Purity

99.13

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=CC=C1)O/N=C2[C@@H]([C@H]([C@@H]([C@H](O/2)CO)O)O)NC(C)=O

Molecular Formula

C15H19N3O7

Molecular Weight

353.33

Precautions

H315, H319, H335

References & Citations

[1]Perreira M, et al. Inhibition of O-GlcNAcase by PUGNAc is dependent upon the oxime stereochemistry. Bioorg Med Chem. 2006;14 (3) :837-846.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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