UBS109

UBS109, as a curcumin analogue, can promote the differentiation and mineralization of osteoblasts. UBS109 shows to regulate bone cell function by activating Smad and inhibiting NF-kB. UBS109 can be used in bone tissue engineering and osteoporosis research[1].

Product Specifications

CAS Number

[1258513-40-4]

UNSPSC

12352005

Target

NF-κB

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ubs109.html

Purity

99.20

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1/C(CN(C)C/C1=C\C2=NC=CC=C2)=C/C3=NC=CC=C3

Molecular Formula

C18H17N3O

Molecular Weight

291.35

References & Citations

[1]Yamaguchi M, et al. Novel curcumin analogue UBS109 potently stimulates osteoblastogenesis and suppresses osteoclastogenesis: involvement in Smad activation and NF-κB inhibition[J]. Integrative biology, 2012, 4 (8) : 905-913.