UBS109
UBS109, as a curcumin analogue, can promote the differentiation and mineralization of osteoblasts. UBS109 shows to regulate bone cell function by activating Smad and inhibiting NF-kB. UBS109 can be used in bone tissue engineering and osteoporosis research[1].
Product Specifications
CAS Number
[1258513-40-4]
UNSPSC
12352005
Target
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ubs109.html
Purity
99.20
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1/C(CN(C)C/C1=C\C2=NC=CC=C2)=C/C3=NC=CC=C3
Molecular Formula
C18H17N3O
Molecular Weight
291.35
References & Citations
[1]Yamaguchi M, et al. Novel curcumin analogue UBS109 potently stimulates osteoblastogenesis and suppresses osteoclastogenesis: involvement in Smad activation and NF-κB inhibition[J]. Integrative biology, 2012, 4 (8) : 905-913.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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