Tesidolumab

Tesidolumab (LFG316) is a fully-human IgG1/λ anti-C5 monoclonal antibody of 143 kDa (without glycosylation) . Tesidolumab (LFG316) blocks cleavage of C5 and prevents subsequent formation of the membrane attack complex[1].

Product Specifications

CAS Number

[1531594-08-7]

Product Name Alternative

LFG316; Anti-Human C5 Recombinant Antibody

UNSPSC

12352203

Target

Complement System

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tesidolumab.html

Purity

98.80

Solubility

10 mM in H2O

Smiles

[Tesidolumab]

Molecular Weight

(142.92 kDa)

References & Citations

[1]Jun-Ichi Nishimura, et al. Tesidolumab (LFG316) for treatment of C5-variant patients with paroxysmal nocturnal hemoglobinuria. Haematologica. 2022 Jun 1;107 (6) :1483-1488.